ABSTRACT
Objective To establish thecontent determination of aloin in Jiehong-Dieda gel paste. Methods The chromatographic column was Kormasi C18 (4.60 mm × 250 mm, 5 μm). The mobile phase was methanol water (45:55) with a rate of 1.0 ml/min. The detection wavelength was set at 355 nm and the column temperature was 30 . ℃ Results Under such condition, the content of aloin was in a good linear relationship within the range of 0.22-1.10 μg(r=0.999 9),and the average recovery was 97.98%(RSD=1.36%).Conclusions The method developed is simple, re1iable and good reproducible. The measurement results can be used as the quality control basis for the preparation process study of Jiehong-Dieda gel paste.
ABSTRACT
Agrimonia pilosa is one of the traditional Chinese herbal medicines for 2000 years history. Due to its various pharmacological effects, it is widely used in the clinical treatment of tumors and other diseases. Presently malignancy has become an important factor threatening human health that the anti-tumor effect of Agrimonia pilosa has attracted great attention. The author reviewed its anti-tumor effect mechanism by articles arrangement of experimental study, clinical study and experience introduction. A series of study revealed 3 mechanisms: blocking cell cycle, inducing apoptosis and strengthening the cellular immunity. As a kind of traditional Chinese herbal medicine which has anti-tumor effect, the Agrimonia pilosa should be reasonably applied according to the related research and previous experience.